Our laboratory is interested in the fundamental programs that regulate glial development and myelination in the developing brain. We study this in vivo and in vitro.

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In Vivo

Examining the role of neuronal activity in neuronal-glial synapse formation and myelination in the murine forebrain

Determining how neuronal inputs regulate oligodendrocyte development and myelination, using synaptic adhesion proteins to perturb synaptic function

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In Vitro:

Using primary neuron- OPC co-cultures to measure OPC maturation and myelination of individual axons