Our laboratory is interested in the fundamental programs that regulate neural circuit formation in the developing brain. We study this in two systems.
In the Vertebrate:
Examining the role of neuronal activity in synapse formation and myelination in the murine forebrain
Determining how synaptic activity affects neural development and myelination, using synaptic adhesion proteins to perturb synaptic function
In the Invertebrate:
Investigating how inhibition regulates circuit formation in the cephalopod visual system by studying inhibitory interneuron development and synapse formation in the retina and optic lobe