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Our laboratory is interested in the fundamental programs that regulate glial development and myelination in the developing brain. We study this in vivo and in vitro.
In Vivo
Examining the role of neuronal activity in neuronal-glial synapse formation and myelination in the murine forebrain
Determining how neuronal inputs regulate oligodendrocyte development and myelination, using synaptic adhesion proteins to perturb synaptic function
In Vitro:
Using primary neuron- OPC co-cultures to measure OPC maturation and myelination of individual axons
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